Our reviews reveals that a serious form of selection bias, miscategorisation, is pervasive throughout the many research studies that aim to measure Covid-19 vaccine efficacy. The effect of this bias is to artificially inflate vaccine efficacy and present the misleading impression that these vaccines are effective and that the non-vaccinated suffer from higher Covid-19 infection rates compared to the vaccinated.We presented a simulation model to demonstrate the effects of this selection bias and show it artificially boosts vaccine efficacy in all cases, and with the application of repeated ‘booster’ vaccinations, the efficacy of repeated Covid-19 vaccines could be maintained at artificial levels in perpetuity should boosting be continued indefinitely. This effect occurs with a both a zero-efficacy (placebo) vaccine and a negative-efficacy vaccine that increases, rather than reduces, infection rates in those vaccinated.This miscategorisation is guaranteed to lead to initially very high efficacy claims (usually above 90%) during peak vaccine rollout even if the vaccine were a placebo or worse. Efficacy then falls toward zero a few weeks later. This pattern of high initial efficacy, tapering off after 3 months is also consistently observed in real-world studies, and is often used as justification for additional, booster vaccinations to maintain efficacy. The corresponding Covid-19 infection rate is also likewise artificially elevated in the unvaccinated cohort compared to the vaccinated cohort. These issues apply to other measures of vaccination effectiveness related to mortality and morbidity.Thus, we conclude that any claims of Covid-19 vaccine efficacy based on these studies are likely to be a statistical illusion
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